Simbios Talk by Daniel Herschlag, Stanford University, April 1, 2009
Title: Finding and Meeting the Challenges in RNA Folding: A Progress Report
I will describe how dissection of simpler and simpler RNAs and model systems can provide rigorous tests of the properties of underlying forces. Further, these simple systems are required for rigorous comparisons of experiment and computation and, in many instances, for meaningful synergy between experiment and computation.
Simbios has stimulated substantial efforts at this interface, although this work represents an initiation rather than a completion of a deep investigation of the physics underlying RNA molecular behavior.