I am a Research Scientist in Russ Altman's group, and have been using molecular dynamics simulations to explore macromolecular structures and interactions. For the Simbios project I am focusing on finding ways to use available experimental data to find structures of macromolecules. The DBP I am working on is addressing the question of how the Tetrahymena Ribozyme (RNA) folds, so in addition to native states we would like to determine structures of short lived intermediate and transition state structures. The experimental data available includes solvent accessible surface area, interatomic distance profiles, and a limited number of interatomic distance constraints.

E-mail: radmer@stanford.edu